EXTEND Trial

A trial to extend breast cancer screening may be unethical.

A trial extending the ages at which UK women are eligible for breast cancer screening was registered in 2010. Its target is “at least” three million participants, with follow-up until “at least the late 2020s.” But was government policy to extend it, regardless of the trial’s findings? Currently, only women aged 50-70 are routinely eligible for breast screening. This trial randomises centres to...

The Extend Adjoint Method

One method to solve topology optimization problems is the topological derivative. This approach has some drawbacks: it is limited to simple problems, we do not know how to fill holes, ... To overcome these limitations, an extension of the adjoint method is presented. Named the numerical vault, it allows us to consider new fields of applications and to explore new theoretical investigations in t...

Proportion Extend Sort

Nature and extend

Some Azomethines of 5-amino isophthalic acid were synthesized and their antibacterial activity was studied in DMSO against four Gram positive Bacillus cereus ATCC11778, Staphylococcus aureus ATCC29737, Staphylococcus epidermidids NCIM2493 and Micrococcus luteus ATCC10240, and three Gram negative bacteria viz. Proteus mirabilis NCIM2241, Escherichia coli ATCC25922 and Klebsiella aerogenes NICM20...

Cytonemes extend their reach.

Cytonemes are specialized filopodia, first described in the Drosophila wing imaginal disc, that were proposed to mediate long distance signalling during development. A recent report from Barna and colleagues (Sanders et al, 2013) published in Nature shows that cytonemes in the chick limb bud carry SHH signalling proteins out to signal receiving cells, thus highlighting their evolutionarily cons...